BDBM345724 1-Cyclopropyl-N-[2-(2-fluoro-6- methyl-phenoxy)-6-(1-methyl-6- oxo-1,6-dihydro-pyridin-3-yl)- pyrimidin-4-yl]- methanesulfonamide::US10202360, Example 269

SMILES Cc1cccc(F)c1Oc1nc(NS(=O)(=O)CC2CC2)cc(n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=RKZYTRLWYBKSGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345724   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345724BDBM345724(US10202360, Example 269 | 1-Cyclopropyl-N-[2-(2-fl...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent