BDBM345739 5-(2-(2-chloro-6-methylphenoxy)-6- (cyclopentylamino)pyrimidin-4-yl)- 1-methylpyridin-2(1H)-one::US10202360, Example 284

SMILES Cc1cccc(Cl)c1Oc1nc(NC2CCCC2)cc(n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=AHVIIZFECDPIHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345739   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345739BDBM345739(US10202360, Example 284 | 5-(2-(2-chloro-6-methylp...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent