BDBM345742 (S)-5-(6-((2,3-dihydro-1H-inden-1- yl)amino)-2-(2-fluoro-6- methylphenoxy)pyrimidin-4-yl)-1- methylpyridin-2(1H)-one::US10202360, Example 287

SMILES Cc1cccc(F)c1Oc1nc(N[C@H]2CCc3ccccc23)cc(n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=OONFYTBZIMATGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345742   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345742BDBM345742(US10202360, Example 287 | (S)-5-(6-((2,3-dihydro-1...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent