BDBM345744 5-(2-(2-fluoro-6-methylphenoxy)-6- (((6-methylpyridin-2- yl)methyl)amino)pyrimidin-4-yl)-1- methylpyridin-2(1H)-one::US10202360, Example 289

SMILES Cc1cccc(CNc2cc(nc(Oc3c(C)cccc3F)n2)-c2ccc(=O)n(C)c2)n1

InChI Key InChIKey=BVTWQSUMUNAUMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345744   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345744BDBM345744(US10202360, Example 289 | 5-(2-(2-fluoro-6-methylp...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent