BDBM345775 2-[4-Benzylamino-6-(1-methyl-6- oxo-1,6-dihydro-pyridin-3-yl)- pyrimidin-2-yloxy]-3-methyl- benzonitrile::US10202360, Example 320

SMILES Cc1cccc(C#N)c1Oc1nc(NCc2ccccc2)cc(n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=HNXAVOPNYXOCES-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345775   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345775BDBM345775(US10202360, Example 320 | 2-[4-Benzylamino-6-(1-me...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent