BDBM345777 (S)-3-Methyl-2-[4-(1-methyl-6-oxo- 1,6-dihydro-pyridin-3-yl)-6-(1- phenyl-ethylamino)-pyrimidin-2- yloxy]-benzonitrile::US10202360, Example 322

SMILES C[C@H](Nc1cc(nc(Oc2c(C)cccc2C#N)n1)-c1ccc(=O)n(C)c1)c1ccccc1

InChI Key InChIKey=MITGJTFIHDSKRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345777   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM345777(US10202360, Example 322 | (S)-3-Methyl-2-[4-(1-met...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent