BDBM345781 5-[2-Methoxy-6-(1-methyl- butylamino)-pyrimidin-4-yl]-1- methyl-1H-pyridin-2-one::US10202360, Example 326

SMILES CCCC(C)Nc1cc(nc(OC)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=QRJLGXUHMUDMRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345781   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345781BDBM345781(US10202360, Example 326 | 5-[2-Methoxy-6-(1-methyl...)
Affinity DataIC50: 2.75E+3nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent