BDBM345790 6-(1,5-dimethyl-6-oxo(3- hydropyridyl))-2-(2,6- dimethylphenoxy)pyrimidine-4- carbonitrile::US10202360, Example 335

SMILES Cc1cccc(C)c1Oc1nc(cc(n1)-c1cc(C)c(=O)n(C)c1)C#N

InChI Key InChIKey=AHXWQKZKGWJXEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345790   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM345790(US10202360, Example 335 | 6-(1,5-dimethyl-6-oxo(3-...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent