BDBM345969 2-(4-Cyclopropylmethyl-1-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-9-ylamino)-N-(2-dimethylamino-ethyl)-N-(3-methyl-pyridin-2-ylmethyl)-acetamide::US10202368, Example 44

SMILES CN(C)CCN(Cc1ncccc1C)C(=O)CNc1cccc2c1N(C)CCN(CC1CC1)C2=O

InChI Key InChIKey=QLVVFBJSPRWUGD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345969   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM345969(US10202368, Example 44 | 2-(4-Cyclopropylmethyl-1-...)
Affinity DataEC50:  130nMAssay Description:The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent