BDBM346538 1,2-dimethylpropyl 4-[3-hydroxy-3-(5-methylisoxazol-3-yl)but-1-ynyl]-2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-3-carboxylate::US10202378, Example 142

SMILES CC(C)C(C)OC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#C[C@@](C)(O)c1cc(C)on1

InChI Key InChIKey=JWXKPARFBSMTNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346538   

LigandPNGBDBM346538(1,2-dimethylpropyl 4-[3-hydroxy-3-(5-methylisoxazo...)
Affinity DataIC50: 52.8nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM346538(1,2-dimethylpropyl 4-[3-hydroxy-3-(5-methylisoxazo...)
Affinity DataIC50: 160nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent