BDBM347259 US10202411, Compound 302

SMILES O[C@@H]1[C@H](CF)[C@@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)O[C@H]1n1ccc(=O)[nH]c1=O

InChI Key InChIKey=BGYFUBIMKSWCFI-UHFFFAOYSA-K

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347259   

TargetGenome polyprotein [S283T](HCV)
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347259(US10202411, Compound 302)
Affinity DataIC50: 250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347259(US10202411, Compound 302)
Affinity DataIC50: 250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent