BDBM347910 US9790221, Compound 116

SMILES Cn1ccc(n1)-c1cnc(nc1NC[C@H]1CCNC[C@H]1O)-c1cccc(c1)-c1cnn(C)c1

InChI Key InChIKey=JCJYOVXKIJNIKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347910   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 347910BDBM347910(US9790221, Compound 116)
Affinity DataIC50: 550nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712). IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1 [194-712](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 347910BDBM347910(US9790221, Compound 116)
Affinity DataIC50: 5.00E+3nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)). In this assay, IRAK-1 hydrolyses ATP and autophosphorylates. Measurement of I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent