BDBM347967 US9790221, Compound 173

SMILES Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2[C@@H]3CN(C[C@H]23)S(C)(=O)=O)n1

InChI Key InChIKey=AQQXBVGVZRVHBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347967   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 347967BDBM347967(US9790221, Compound 173)
Affinity DataIC50: 550nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712). IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1 [194-712](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 347967BDBM347967(US9790221, Compound 173)
Affinity DataIC50: 5.00E+3nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)). In this assay, IRAK-1 hydrolyses ATP and autophosphorylates. Measurement of I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent