BDBM348904 (4R)-4-methyl-6-[(E)-2-(1-methylpyrazol-4-yl)vinyl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one::US10206931, Example 4

SMILES CN\C=C(/C=N)\C=C\c1cccc2NC(=O)C[C@@H](C)Nc12

InChI Key InChIKey=DIOXQGUGYPSIRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 348904   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 348904BDBM348904((4R)-4-methyl-6-[(E)-2-(1-methylpyrazol-4-yl)vinyl...)
Affinity DataIC50: 586nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent