BDBM349213 N-[4-[(E)-2-[(4R)-4-methyl-2-oxo-1,3,4,5-tetrahydro-1,5-benzodiazepin-6-yl]vinyl]phenyl]acetamide::US10206931, Example 20

SMILES C[C@@H]1CC(=O)Nc2cccc(\C=C\c3ccc(NC(C)=O)cc3)c2N1

InChI Key InChIKey=ZKQLHJHNQHBLCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 349213   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 349213BDBM349213(N-[4-[(E)-2-[(4R)-4-methyl-2-oxo-1,3,4,5-tetrahydr...)
Affinity DataIC50: 221nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent