BDBM349236 (4R)-6-[1-(4-fluorophenyl)sulfonylindol-2-yl]-4-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one::US10206931, Example 43

SMILES C[C@@H]1CC(=O)Nc2cccc(-c3cc4ccccc4n3S(=O)(=O)c3ccc(F)cc3)c2N1

InChI Key InChIKey=COQNQAWLVQTGGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 349236   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 349236BDBM349236((4R)-6-[1-(4-fluorophenyl)sulfonylindol-2-yl]-4-me...)
Affinity DataIC50: 440nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent