BDBM349613 (3-(4-(2-(azepan-1-yl)ethoxy)phenoxy)- 6-hydroxybenzo[b]thiophen-2-yl)(4- fluoro-2,6-dimethylphenyl)methanone::US10208011, Compound 107::US10981887, Compound 107

SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CCCCCC2)cc1

InChI Key InChIKey=UYANDZCLTSLUGR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 349613   

TargetEstrogen receptor(Human)
G1 Therapeutics

US Patent
LigandPNGBDBM349613((3-(4-(2-(azepan-1-yl)ethoxy)phenoxy)- 6-hydroxybe...)
Affinity DataIC50: 1.00E+3nMAssay Description:A screening strategy was implemented utilizing an In-Cell Western assay to measure their ability to degrade the estrogen receptor in vitro. MCF7 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent

TargetG-protein coupled estrogen receptor 1(Human)
G1 Therapeutics

US Patent
LigandPNGBDBM349613((3-(4-(2-(azepan-1-yl)ethoxy)phenoxy)- 6-hydroxybe...)
Affinity DataIC50: 1.00E+3nMAssay Description:All reagents used in this assay was supplied in the Human ERα Reporter Assay by Indigo Biosciences # IB00401. In an effort to screen selective e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetG-protein coupled estrogen receptor 1(Human)
G1 Therapeutics

US Patent
LigandPNGBDBM349613((3-(4-(2-(azepan-1-yl)ethoxy)phenoxy)- 6-hydroxybe...)
Affinity DataIC50: 1.00E+3nMAssay Description:A screening strategy was implemented utilizing an In-Cell Western assay to measure their ability to degrade the estrogen receptor in vitro. MCF7 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
G1 Therapeutics

US Patent
LigandPNGBDBM349613((3-(4-(2-(azepan-1-yl)ethoxy)phenoxy)- 6-hydroxybe...)
Affinity DataIC50: 1.00E+3nMAssay Description:All reagents used in this assay was supplied in the Human ERα Reporter Assay by Indigo Biosciences #IB00401. In an effort to screen selective es...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent