BDBM349676 US10208019, Example 1A-23::rac-2-{[(3S,4S)-4-{6-[(4-chloro-2-fluorobenzyl)oxy]pyridin-2-yl}-3-hydroxypiperidin-1-yl]methyl}-1-(2-methoxyethyl)-1H-benzimidazole-6-carboxylic acid

SMILES COCCn1c(CN2CC[C@H]([C@H](O)C2)c2cccc(OCc3ccc(Cl)cc3F)n2)nc2ccc(cc12)C(O)=O

InChI Key InChIKey=JMBWEJQHPLSOAE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 349676   

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM349676(rac-2-{[(3S,4S)-4-{6-[(4-chloro-2-fluorobenzyl)oxy...)
Affinity DataEC50:  50nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM349676(rac-2-{[(3S,4S)-4-{6-[(4-chloro-2-fluorobenzyl)oxy...)
Affinity DataEC50:  1.00E+3nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent