BDBM34985 benzothienopyrimidinone deriv., 6b

SMILES O=c1[nH]c(CN2CCCCC2)nc2c1sc1ccc(Cl)cc12

InChI Key InChIKey=DJOXKKRRSXGVNT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34985   

TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 34985BDBM34985(benzothienopyrimidinone deriv., 6b)
Affinity DataKi:  12nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 34985BDBM34985(benzothienopyrimidinone deriv., 6b)
Affinity DataKi:  149nM ΔG°:  -9.31kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed