BDBM35044 benzothienopyrimidinone deriv., 19b

SMILES Oc1cccc(NCc2nc3c4cc(ccc4sc3c(=O)[nH]2)-c2ccsc2)c1

InChI Key InChIKey=VNMVTYUOFYWKCY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35044   

TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

LigandPNGBDBM35044(benzothienopyrimidinone deriv., 19b)
Affinity DataKi:  2nM ΔG°:  -11.9kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Abbott Laboratories

LigandPNGBDBM35044(benzothienopyrimidinone deriv., 19b)
Affinity DataKi:  152nM ΔG°:  -9.29kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed