BDBM35065 N-acylpolyamine (NAPA) scaffold, 12

SMILES COc1ccc(CCCNC(=O)N(CCC(N)=O)CC(CCC(O)=O)N(CC(CCCCN)N(CC(CCC(O)=O)NC(N)=O)C(=O)NCCCC(C)C)C(=O)NCCc2ccc(Br)cc2)cc1

InChI Key InChIKey=QKDNAMJGIDZDMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35065   

LigandPNGBDBM35065(N-acylpolyamine (NAPA) scaffold, 12)
Affinity DataIC50: 1.00E+5nMpH: 7.6 T: 2°CAssay Description:Inhibitory activities of NAPAs were measured by fluorescence anisotropy competition experiments. Protein was incubated with fluorescein-labeled huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Nih

LigandPNGBDBM35065(N-acylpolyamine (NAPA) scaffold, 12)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activities of NAPAs were measured by fluorescence anisotropy competition experiments. Protein was incubated with fluorescein-labeled huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed