BDBM35071 N-acylpolyamine (NAPA) scaffold, 18

SMILES NCCCCC(CN(C(CCC(O)=O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1)C(=O)NCCc1ccc(Br)cc1)N(CC(CCC(O)=O)NC(N)=O)C(=O)NCCCC1CCCCC1

InChI Key InChIKey=HNLKTYSAPFGWPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35071   

LigandPNGBDBM35071(N-acylpolyamine (NAPA) scaffold, 18)
Affinity DataIC50: 6.40E+3nMpH: 7.6 T: 2°CAssay Description:Inhibitory activities of NAPAs were measured by fluorescence anisotropy competition experiments. Protein was incubated with fluorescein-labeled huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Nih

LigandPNGBDBM35071(N-acylpolyamine (NAPA) scaffold, 18)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibitory activities of NAPAs were measured by fluorescence anisotropy competition experiments. Protein was incubated with fluorescein-labeled huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed