BDBM351283 N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 9

SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1

InChI Key InChIKey=HVXKQKFEHMGHSL-QDMKHBRRSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 351283   

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetVascular endothelial growth factor receptor 1(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351283(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In DepthDetails US Patent