BDBM351296 N-(3,4-dichloro-2-fluorophenyl)-7-{[(3S,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 22

SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1

InChI Key InChIKey=ABXIBRWZRWHJCZ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 351296   

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 1(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandChemical structure of BindingDB Monomer ID 351296BDBM351296(US9796704, Entry 22 | N-(3,4-dichloro-2-fluorophen...)
Affinity DataIC50: 1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent