BDBM35140 5-vinyl-3-pyridinecarbonitrile, 22

SMILES Cc1c(Nc2c(\C=C\CCN3CC[C@@H](N)C3)cncc2C#N)ccc2[nH]ccc12

InChI Key InChIKey=DNZGKSANTHABGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35140   

TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM35140(5-vinyl-3-pyridinecarbonitrile, 22)
Affinity DataIC50: 3.5nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

LigandPNGBDBM35140(5-vinyl-3-pyridinecarbonitrile, 22)
Affinity DataIC50: 15nMAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2009
Entry Details Article
PubMed