BDBM351438 N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- phenyl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 158

SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nsc(n1)-c1ccccc1

InChI Key InChIKey=YNRDGUQMVYIVCM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 351438   

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351438(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- pheny...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351438(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- pheny...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351438(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- pheny...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351438(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- pheny...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent