BDBM352022 US9802904, 83

SMILES Cc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-c2nnn[nH]2)cc1

InChI Key InChIKey=XGQQSJMKAJKQQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 352022   

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 352022BDBM352022(US9802904, 83)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 352022BDBM352022(US9802904, 83)
Affinity DataIC50: 7.60E+3nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent