BDBM35253 3-(phenylsulfonyl)-1H-indole, 33c

SMILES O=S(=O)(c1c[nH]c2cccc(CCCN3CCCCC3)c12)c1ccccc1

InChI Key InChIKey=IZXAGSUHTCPYKG-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35253   

LigandPNGBDBM35253(3-(phenylsulfonyl)-1H-indole, 33c)
Affinity DataKi:  1.03E+3nM ΔG°:  -8.49kcal/mole IC50: 707nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandPNGBDBM35253(3-(phenylsulfonyl)-1H-indole, 33c)
Affinity DataKi:  854nM IC50: 7.97E+3nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed