BDBM353026 N-(4-Hydroxyphenyl)-5-{2-[2-(4-methoxyphenyl)acetyl]-6-[(3R)-3-methyl-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]-2,3-dihydro-1H-isoindol-5-yl}-N,1,2-trimethyl-1H-pyrrole-3-carboxamide::US9809574, Example 101

SMILES COc1ccc(CC(=O)N2Cc3cc(C(=O)N4Cc5ccccc5C[C@H]4C)c(cc3C2)-c2cc(C(=O)N(C)c3ccc(O)cc3)c(C)n2C)cc1

InChI Key InChIKey=MUBDETCPNUIMOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353026   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM353026(US9809574, Example 101 | N-(4-Hydroxyphenyl)-5-{2-...)
Affinity DataIC50: 2.60nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
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Date in BDB:
10/7/2019
Entry Details
US Patent