BDBM353829 US9796708, Example 1061::methyl {4-[4-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}acetate

SMILES COC(=O)CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1ccccc1OC

InChI Key InChIKey=QMWPLSYCMVAAIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353829   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 353829BDBM353829(methyl {4-[4-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]py...)
Affinity DataIC50: 180nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent