BDBM3552 CHEMBL65038::N-(3-bromophenyl)-7-methoxy-6-nitroquinazolin-4-amine::PD153035 Analog 52

SMILES COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+]([O-])=O

InChI Key InChIKey=CZBTZBBBQGIOGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3552   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3552(CHEMBL65038 | N-(3-bromophenyl)-7-methoxy-6-nitroq...)
Affinity DataIC50: 15nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3552(CHEMBL65038 | N-(3-bromophenyl)-7-methoxy-6-nitroq...)
Affinity DataIC50: 15nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM3552(CHEMBL65038 | N-(3-bromophenyl)-7-methoxy-6-nitroq...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed