BDBM355454 N-{(1R)-1-[2-fluoro-4- (trifluoromethyl)phenyl]-2,2- dimethylpropyl}-6-oxo-2-phenyl- 1,6-dihydropyrimidine-4- carboxamide::US9815796, Example 545

SMILES CC(C)(C)[C@@H](NC(=O)c1cc(=O)[nH]c(n1)-c1ccccc1)c1ccc(cc1F)C(F)(F)F

InChI Key InChIKey=LOJROMAPKUYJRZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355454   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355454(US9815796, Example 545 | N-{(1R)-1-[2-fluoro-4- (t...)
Affinity DataKi:  1.20nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
US Patent