BDBM355895 1-(2-chloro-7- isopropylpyrazolo[1, 5-a]pyrimidin-6-yl)-3- (3-cyano-4-(3- methyl-1H-1,2,4- triazol-1- yl)phenyl)urea::US10442808, Example 19::US9815842, Example 19

SMILES CC(C)c1c(NC(=O)Nc2ccc(c(c2)C#N)-n2cnc(C)n2)cnc2cc(Cl)nn12

InChI Key InChIKey=ASKGTNQOKQTCEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355895   

LigandPNGBDBM355895(US9815842, Example 19 | 1-(2-chloro-7- isopropylpy...)
Affinity DataIC50: 0.00300nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

LigandPNGBDBM355895(US9815842, Example 19 | 1-(2-chloro-7- isopropylpy...)
Affinity DataIC50: 0.00300nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
US Patent