BDBM3561 4-[(3-Bromophenyl)amino]-6,7-dimethoxy-2-methylquinazoline Hydrochloride::CHEMBL294769::N-(3-bromophenyl)-6,7-dimethoxy-2-methylquinazolin-4-amine::PD153035 Analog::PD153035 Analog 61

SMILES COc1cc2nc(C)nc(Nc3cccc(Br)c3)c2cc1OC

InChI Key InChIKey=YDJAVBPPDOYWGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3561   

TargetFructose-1,6-bisphosphatase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM3561(N-(3-bromophenyl)-6,7-dimethoxy-2-methylquinazolin...)
Affinity DataIC50: 4.50E+3nMAssay Description:Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3561(N-(3-bromophenyl)-6,7-dimethoxy-2-methylquinazolin...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed