BDBM356563 N-[3-(7-{6-[4-(Cyclopentylacetyl)piperazin-1-yl]pyridin-3-yl}imidazo[1,2-b]pyridazin-3-yl)phenyl]-N′-(2,2,2-trifluoroethyl)urea::US10213427, Example 52::US10813930, Ex. No. 52

SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(cnn12)-c1ccc(nc1)N1CCN(CC1)C(=O)CC1CCCC1

InChI Key InChIKey=ZTDNZZRENNGQGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356563   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 356563BDBM356563(N-[3-(7-{6-[4-(Cyclopentylacetyl)piperazin-1-yl]py...)
Affinity DataIC50: 13nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 356563BDBM356563(N-[3-(7-{6-[4-(Cyclopentylacetyl)piperazin-1-yl]py...)
Affinity DataIC50: 17.5nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent