BDBM357757 KM-05-55 Fr16-17/(I-7)::US10214530, Example 7

SMILES CC(=O)Nc1ccc2nc(Cc3nc4n(C)c(=O)[nH]c(=O)c4n3Cc3ccccc3)[nH]c2c1

InChI Key InChIKey=JBVSGHJSCYWOJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357757   

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandPNGBDBM357757(KM-05-55 Fr16-17/(I-7) | US10214530, Example 7)
Affinity DataIC50: 290nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandPNGBDBM357757(KM-05-55 Fr16-17/(I-7) | US10214530, Example 7)
Affinity DataIC50: 4.11E+3nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent