BDBM358072 ((2S,4R)-2-(3-(4-Amino-5-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl) pyrrolo[2,1-f][1,2,4]triazin-7-yl)phenyl)-4-hydroxypyrrolidin-1-yl)(cyclopropyl)methanone::US10214537, Example 141

SMILES Nc1ncnn2c(cc(-c3ccnn3C3CCOCC3)c12)-c1cccc(c1)[C@@H]1C[C@@H](O)CN1C(=O)C1CC1

InChI Key InChIKey=HQNVTLVVGHHAOG-QPPBQGQZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358072   

LigandPNGBDBM358072(((2S,4R)-2-(3-(4-Amino-5-(1-(tetrahydro-2H-pyran-4...)
Affinity DataIC50:  0.5nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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