BDBM358596 (S)-4-acetyl-1-(5-(4-amino-5- (trifluoromethyl)pyrrolo[2,1-f][1,2,4] triazin-7-yl)-2-(methylsulfonyl) phenyl)-3,3,6-trimethylpiperazin-2-one::US10214537, Example 673::US10214537, Example 674

SMILES C[C@H]1CN(C(C)=O)C(C)(C)C(=O)N1c1cc(ccc1S(C)(=O)=O)-c1cc(c2c(N)ncnn12)C(F)(F)F

InChI Key InChIKey=XHZVABMGYLGFIJ-LBPRGKRZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 358596   

LigandPNGBDBM358596((S)-4-acetyl-1-(5-(4-amino-5- (trifluoromethyl)pyr...)
Affinity DataIC50:  0.900nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM358596((S)-4-acetyl-1-(5-(4-amino-5- (trifluoromethyl)pyr...)
Affinity DataIC50:  0.600nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent