BDBM358605 (S)-7-(3-(4-acetyl-3,3,6-trimethyl-2- oxopiperazin-1-yl)-4-fluorophenyl)-4- aminopyrrolo[2,1-f][1,2,4]triazine-5- carbonitrile::US10214537, Example 682

SMILES C[C@H]1CN(C(C)=O)C(C)(C)C(=O)N1c1cc(ccc1F)-c1cc(C#N)c2c(N)ncnn12

InChI Key InChIKey=RMJDHMBGJKUPQX-LBPRGKRZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358605   

LigandPNGBDBM358605((S)-7-(3-(4-acetyl-3,3,6-trimethyl-2- oxopiperazin...)
Affinity DataIC50:  0.400nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent