BDBM358609 2-(4-acetyl-3-ethyl-3-methyl-2- oxopiperazin-1-yl)-4-(4-amino-5- (trifluoromethyl)pyrrolo[2,1-f][1,2,4] triazin-7-yl)benzonitrile::US10214537, Example 686

SMILES CCC1(C)N(CCN(C1=O)c1cc(ccc1C#N)-c1cc(c2c(N)ncnn12)C(F)(F)F)C(C)=O

InChI Key InChIKey=SUWKCHNZMCPEFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358609   

LigandPNGBDBM358609(2-(4-acetyl-3-ethyl-3-methyl-2- oxopiperazin-1-yl)...)
Affinity DataIC50:  0.300nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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