BDBM358665 4-(4-amino-5-chloropyrrolo[2,1-f] [1,2,4]triazin-7-yl)-2-(3,3-dimethyl-4- (3-(3-methyl-1H-pyrazol-1- yl)propanoyl)-2-oxopiperazin-1- yl)benzonnitrile::US10214537, Example 742
SMILES Cc1ccn(CCC(=O)N2CCN(C(=O)C2(C)C)c2cc(ccc2C#N)-c2cc(Cl)c3c(N)ncnn23)n1
InChI Key InChIKey=SSUIICBDLSZQSI-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358665
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 0.700nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair