BDBM358684 1-(3-(4-amino-5-chloropyrrolo[2,1-f] [1,2,4]triazin-7-yl)phenyl)-4-(3- hydroxy-3-methylbutanoyl)-3,3- dimethylpiperazin-2-one::US10214537, Example 762
SMILES CC(C)(O)CC(=O)N1CCN(C(=O)C1(C)C)c1cccc(c1)-c1cc(Cl)c2c(N)ncnn12
InChI Key InChIKey=LSWYOMHSKRIWPA-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358684
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 0.200nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair