BDBM358685 (S)-4-(4-amino-5-chloropyrrolo[2,1-f] [1,2,4]triazin-7-yl)-2-(3,3,6-trimethyl- 4-(2-(methylsulfonyl)acetyl)-2- oxopiperazin-1-yl)benzonitrile::US10214537, Example 763

SMILES C[C@H]1CN(C(=O)CS(C)(=O)=O)C(C)(C)C(=O)N1c1cc(ccc1C#N)-c1cc(Cl)c2c(N)ncnn12

InChI Key InChIKey=AMCBJLGFWBNMTM-ZDUSSCGKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358685   

LigandPNGBDBM358685((S)-4-(4-amino-5-chloropyrrolo[2,1-f] [1,2,4]triaz...)
Affinity DataIC50:  0.5nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent