BDBM358689 1-(5-(4-amino-5-(trifluoromethyl) pyrrolo[2,1-f][1,2,4]triazin-7-yl)-2- methoxyphenyl)-3,3-dimethyl-4-(2- (methylsulfonyl)propanoyl)piperazin- 2-one::US10214537, Example 767

SMILES COc1ccc(cc1N1CCN(C(=O)C(C)S(C)(=O)=O)C(C)(C)C1=O)-c1cc(c2c(N)ncnn12)C(F)(F)F

InChI Key InChIKey=CULPQCPKYXLOSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358689   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM358689(1-(5-(4-amino-5-(trifluoromethyl) pyrrolo[2,1-f][1...)
Affinity DataIC50:  0.700nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent