BDBM358739 (S)-4-acetyl-1-(5-(4-amino-5- chloropyrrolo[2,1-f][1,2,4]triazin-7- yl)-2-(1-hydroxypropyl)phenyl)-3,3- dimethylpiperazin-2-one::US10214537, Example 818
SMILES CC[C@H](O)c1ccc(cc1N1CCN(C(C)=O)C(C)(C)C1=O)-c1cc(Cl)c2c(N)ncnn12
InChI Key InChIKey=FFJRTAZXXLSBIY-IBGZPJMESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358739
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 0.5nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair