BDBM359185 US10220048, Compound AA95::US10952992, No. AA95::US11413242, Compound AA95::US11666558, Example AA95

SMILES Cc1nnc(N[C@@H](Cc2ccc(NS(O)(=O)=O)cc2)c2csc(n2)-c2ccccc2)s1

InChI Key InChIKey=BNMPXZKWADCLTR-KRWDZBQOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 359185   

TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359185(US10220048, Compound AA95 | US10952992, No. AA95 |...)
Affinity DataIC50:  3nMAssay Description:HPTP-β inhibition can be tested by any method chosen by the formulator, for example, Amarasinge K. K. et al., “Design and Synthesis of Potent, N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359185(US10220048, Compound AA95 | US10952992, No. AA95 |...)
Affinity DataIC50:  3nMAssay Description:Non-limiting examples of the HPTP-β IC50(μM) activity for illustrative compounds are listed in TABLE 2.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359185(US10220048, Compound AA95 | US10952992, No. AA95 |...)
Affinity DataIC50:  3nMAssay Description:Non-limiting examples of the HPTPβ IC50 (μM) activity.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359185(US10220048, Compound AA95 | US10952992, No. AA95 |...)
Affinity DataIC50:  3nMAssay Description:Non-limiting examples of the HPTP-β IC50 (μM) activity.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent