BDBM35946 4-pyridinoxy-2-anilinopyridine-based compound, 10

SMILES COc1ccccc1Nc1cc(Oc2cc(C)c(C)nc2-c2ccccn2)ccn1

InChI Key InChIKey=TWHDGQOWPWNNCU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35946   

TargetTGF-beta receptor type-1(Human)
Astrazeneca

LigandPNGBDBM35946(4-pyridinoxy-2-anilinopyridine-based compound, 10)
Affinity DataIC50: 7nM EC50:  114nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization assay was used to assess the ALK5 binding capacity and biochemical activity of compounds. ALK5 protein was added to each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed