BDBM359718 US10435355, Example 2::US9822068, 2::[4-fluoro-3-(3- sulfamoylphenyl)phenyl] N-cyclohexylcarbamate

SMILES NS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1F

InChI Key InChIKey=FILLCJRGEZQEBM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 359718   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University of California

US Patent
LigandPNGBDBM359718(US10435355, Example 2 | US9822068, 2 | [4-fluoro-3...)
Affinity DataIC50:  0.700nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM359718(US10435355, Example 2 | US9822068, 2 | [4-fluoro-3...)
Affinity DataIC50:  11nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University of California

US Patent
LigandPNGBDBM359718(US10435355, Example 2 | US9822068, 2 | [4-fluoro-3...)
Affinity DataIC50:  0.700nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM359718(US10435355, Example 2 | US9822068, 2 | [4-fluoro-3...)
Affinity DataIC50:  11nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent