BDBM362759 N-[6-[(2R)-Morpholin-2-yl]-3-pyridyl]-4-(trifluoromethyl)benzamide::US9840501, Example 53

SMILES FC(F)(F)c1ccc(cc1)C(=O)Nc1ccc(nc1)[C@H]1CNCCO1

InChI Key InChIKey=BXTUVKRZTXUOOF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362759   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 362759BDBM362759(US9840501, Example 53 | N-[6-[(2R)-Morpholin-2-yl]...)
Affinity DataKi:  6.10nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 362759BDBM362759(US9840501, Example 53 | N-[6-[(2R)-Morpholin-2-yl]...)
Affinity DataKi:  71.8nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent