BDBM362864 2-(5-methylpyridin-3-yl)-5-oxo-4,5,6,7- tetrahydropyrazolo[1,5-a]pyrimidine-3- carbonitrile::US9844553, 25

SMILES Cc1cncc(c1)-c1nn2CCC(=O)Nc2c1C#N

InChI Key InChIKey=HWPJVYVRGQRDSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362864   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362864(US9844553, 25 | 2-(5-methylpyridin-3-yl)-5-oxo-4,5...)
Affinity DataIC50: 61nMAssay Description:Methods for V79-Human-CYP11B2 and V79-Human-CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent